The ammp-8 stands for Activated Metallic Matrix Proteinase 8. This ammp-8 is a marker enzyme that is linked to destructive or remodelling processes in the tissue, mainly linked to matrix molecules like elastin and collagen. Both elastin and even more collagen play a mayor role in periodontitis since these molecules are destroyed by bacteria in the oral cavity thru endotoxins and acids. As we rely on scientific data we know that Periodontitis is linked to many general/chronic diseases like diabetes, rheumatism, osteoporosis, heart problems etc. A little sample of saliva from the patient is put into a small chromatograph and within 10 minutes we have the result, it works actually like a pregnancy test.